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Published January 1, 2009 | Version v1
Journal article Open

Angiotensin-converting enzyme insertion/deletion polymorphism has no effect on the risk of atherosclerotic stroke or hypertension

Creators

  • 1. Zonguldak Karaelmas Univ, Fac Med, Dept Neurol, Zonguldak, Turkey
  • 2. Zonguldak Karaelmas Univ, Fac Med, Dept Genet, Zonguldak, Turkey
  • 3. Zonguldak Karaelmas Univ, Fac Med, Dept Biostat, Zonguldak, Turkey
  • 4. Zonguldak Karaelmas Univ, Fac Med, Dept Biochem, Zonguldak, Turkey

Description

Background and purpose: Stroke is a heterogeneous multifactorial disease. Hence, a large number of candidate genes are involved in stroke pathophysiology, such as blood pressure regulation and atherosclerosis. Although angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism is considered to have a role in hypertension, coronary artery disease, and myocardial infarction, its relationship with cerebrovascular disease and hypertension in Stroke in different ethnic populations is still inconsistent.

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