Published January 1, 2018
| Version v1
Journal article
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Studies on non-steroidal inhibitors of aromatase enzyme; 4-(aryl/heteroaryl)-2-(pyrimidin-2-yl)thiazole derivatives
Creators
- 1. Istanbul Medipol Univ, Sch Pharm, Dept Pharmaceut Chem, TR-34083 Istanbul, Turkey
- 2. Istanbul Medipol Univ, Sch Pharm, Dept Pharmaceut Microbiol, TR-34083 Istanbul, Turkey
- 3. Anadolu Univ, Dept Pharmaceut Chem, Fac Pharm, TR-26470 Eskisehir, Turkey
Description
Steroidal and non-steroidal aromatase inhibitors target the suppression of estrogen biosynthesis in the treatment of breast cancer. Researchers have increasingly focused on developing non-steroidal derivatives for their potential clinical use avoiding steroidal side-effects.
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