Published January 1, 2018 | Version v1
Journal article Open

MicroRNA-221/222 expression in atherosclerotic coronary artery plaque versus internal mammarian artery and in peripheral blood samples

  • 1. Cumhuriyet Univ, Fac Med, Dept Med Biol, Sivas, Turkey
  • 2. Cumhuriyet Univ, Fac Sci, Dept Mol Biol & Genet, Sivas, Turkey
  • 3. Cumhuriyet Univ, Fac Med, Dept Cardiovasc Surg, Sivas, Turkey
  • 4. Cumhuriyet Univ, Fac Med, Dept Cardiol, TR-58140 Sivas, Turkey

Description

Background: Atherosclerosis is a disease of the arterial wall with predilection to some sites on others. MicroRNAs (miRNAs) are a class of the non-coding RNAs regulating the target gene expression at post-transcriptional level. Different miRNAs were found at distinct stages of plaque development and expression of miRNAs' might play an important role in the local behaviour of atherosclerotic plaques.

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