Published January 1, 2018 | Version v1
Journal article Open

Exploring the Clinical and Genetic Spectrum of Steroid Resistant Nephrotic Syndrome: The PodoNet Registry

  • 1. Univ Ctr Pediat & Adolescent Med, Div Pediat Nephrol, Heidelberg, Germany
  • 2. Med Univ Gdansk, Dept Biol & Med Genet, Clin Genet Unit, Gdansk, Poland

Description

Background: Steroid resistant nephrotic syndrome (SRNS) is a rare condition, accounting for 10-15% of all children with idiopathic nephrotic syndrome. SRNS can be caused by genetic abnormalities or immune system dysfunction. The prognosis of SRNS varies from permanent remission to progression to end-stage kidney disease, and post-transplant recurrence is common.

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