Published January 1, 2010 | Version v1
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Effects of levobupivacaine and bupivacaine on intracellular calcium signaling in cultured rat dorsal root ganglion neurons

  • 1. Firat Univ, Dept Biophys, Fac Med, TR-23169 Elazig, Turkey
  • 2. Karadeniz Tech Univ, Dept Physiol, Fac Med, TR-23119 Trabzon, Turkey
  • 3. Firat Univ, Dept Physiol, Fac Med, TR-23169 Elazig, Turkey
  • 4. Firat Univ, Dept Anaesthesiol, Fac Med, TR-23169 Elazig, Turkey

Description

Bupivacaine and levobupivacaine have been shown to be effective in the treatment of pain as local anesthetics, although the mechanisms mediating their antinociceptive actions are still not well understood. The aim of this study was to investigate the effects of bupivacaine and levobupivacaine on intracellular calcium ([Ca

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