Published January 1, 2018
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Striatal Neurotransmitter Release-related Presynaptic Proteins in L-dopa Induced Dyskinesia in a Model of Parkinsonism
- 1. Hacettepe Univ, Inst Neurol Sci & Psychiat, Ankara, Turkey
- 2. Hacettepe Univ, Sch Med, Dept Neurol, Ankara, Turkey
Description
Introduction: In Parkinson's disease, L-dopa-induced dyskinesia (LID) and motor fluctuations incapacitate patients as much as the disease itself. Many studies demonstrated that postsynaptic alterations and striatal synaptic plasticity changes play a role in LID development. Here, we aimed to study the role of striatal presynaptic proteins in LID pathogenesis.
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