1 Ocak 2020 Dergi makalesi Açık Erişim

Celebi, Asuman; Orhan, Ceren; Seyhan, Betul; Buyru, Nur

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/8703</identifier>
  <creators>
    <creator>
      <creatorName>Celebi, Asuman</creatorName>
      <givenName>Asuman</givenName>
      <familyName>Celebi</familyName>
      <affiliation>Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Med Biol &amp; Genet, Kocamustafapasa, TR-34098 Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Orhan, Ceren</creatorName>
      <givenName>Ceren</givenName>
      <familyName>Orhan</familyName>
      <affiliation>Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Med Biol &amp; Genet, Kocamustafapasa, TR-34098 Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Seyhan, Betul</creatorName>
      <givenName>Betul</givenName>
      <familyName>Seyhan</familyName>
      <affiliation>Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Med Biol &amp; Genet, Kocamustafapasa, TR-34098 Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Buyru, Nur</creatorName>
      <givenName>Nur</givenName>
      <familyName>Buyru</familyName>
      <affiliation>Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Med Biol &amp; Genet, Kocamustafapasa, TR-34098 Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Silencing Of Wwox Increases Nuclear Import Of Dvl Proteins In Head And Neck Cancer</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2020</publicationYear>
  <dates>
    <date dateType="Issued">2020-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/8703</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.7150/jca.40840</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Background: Wnt signaling pathway is associated with a variety of human cancers, including HNSCC. Wnt proteins control cellular events such as proliferation, fate specification, polarity, and migration by transducing signals to the nucleus through several cytoplasmic relay proteins. Although activation of the Wnt/beta-catenin pathway is a frequent event in various cancers, there is limited knowledge on the contribution of this signaling mechanism in HNSCC. The Wwox tumor suppressor protein participates in the regulation of Wnt signaling by interacting with Dvl proteins.</description>
  </descriptions>
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