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M.", "name": "Gulaldi, Nedim C. M.", "type": "personal" } }, { "affiliations": [ { "name": "Johns Hopkins Sch Med, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA" } ], "person_or_org": { "family_name": "Szabo", "given_name": "Zsolt", "name": "Szabo, Zsolt", "type": "personal" } } ], "description": "Purpose: The radioligand C-11-KR31173 has been introduced for positron emission tomography (PET) imaging of the angiotensin II subtype 1 receptor in the kidney in vivo. To study the biokinetics of C-11-KR31173 with a compartmental model, the input function is needed. Collection and analysis of arterial blood samples are the established approach to obtain the input function but they are not feasible in patients with renal diseases. 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