1 Ocak 2019 Dergi makalesi Açık Erişim

Altinelataman, Can; Koroleva, Olga; Fedorova, Tatyana; Torkova, Anna; Lisitskaya, Ksenia; Tsentalovich, Mikhail; Kononikhin, Aleksey; Popov, Igor; Vasina, Dania; Kovalyov, Leonid; Celik, Ufuk

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/67903</identifier>
  <creators>
    <creator>
      <creatorName>Altinelataman, Can</creatorName>
      <givenName>Can</givenName>
      <familyName>Altinelataman</familyName>
      <affiliation>Ege Univ, Fac Fisheries, TR-35100 Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Koroleva, Olga</creatorName>
      <givenName>Olga</givenName>
      <familyName>Koroleva</familyName>
      <affiliation>Russian Acad Sci, Res Ctr Biotechnol, 33,Bld 2,Leninsky Ave, Moscow 119071, Russia</affiliation>
    </creator>
    <creator>
      <creatorName>Fedorova, Tatyana</creatorName>
      <givenName>Tatyana</givenName>
      <familyName>Fedorova</familyName>
      <affiliation>Russian Acad Sci, Res Ctr Biotechnol, 33,Bld 2,Leninsky Ave, Moscow 119071, Russia</affiliation>
    </creator>
    <creator>
      <creatorName>Torkova, Anna</creatorName>
      <givenName>Anna</givenName>
      <familyName>Torkova</familyName>
      <affiliation>Russian Acad Sci, Res Ctr Biotechnol, 33,Bld 2,Leninsky Ave, Moscow 119071, Russia</affiliation>
    </creator>
    <creator>
      <creatorName>Lisitskaya, Ksenia</creatorName>
      <givenName>Ksenia</givenName>
      <familyName>Lisitskaya</familyName>
      <affiliation>Russian Acad Sci, Res Ctr Biotechnol, 33,Bld 2,Leninsky Ave, Moscow 119071, Russia</affiliation>
    </creator>
    <creator>
      <creatorName>Tsentalovich, Mikhail</creatorName>
      <givenName>Mikhail</givenName>
      <familyName>Tsentalovich</familyName>
      <affiliation>Russian Acad Sci, Res Ctr Biotechnol, 33,Bld 2,Leninsky Ave, Moscow 119071, Russia</affiliation>
    </creator>
    <creator>
      <creatorName>Kononikhin, Aleksey</creatorName>
      <givenName>Aleksey</givenName>
      <familyName>Kononikhin</familyName>
    </creator>
    <creator>
      <creatorName>Popov, Igor</creatorName>
      <givenName>Igor</givenName>
      <familyName>Popov</familyName>
    </creator>
    <creator>
      <creatorName>Vasina, Dania</creatorName>
      <givenName>Dania</givenName>
      <familyName>Vasina</familyName>
      <affiliation>Russian Acad Sci, Res Ctr Biotechnol, 33,Bld 2,Leninsky Ave, Moscow 119071, Russia</affiliation>
    </creator>
    <creator>
      <creatorName>Kovalyov, Leonid</creatorName>
      <givenName>Leonid</givenName>
      <familyName>Kovalyov</familyName>
      <affiliation>Russian Acad Sci, Res Ctr Biotechnol, 33,Bld 2,Leninsky Ave, Moscow 119071, Russia</affiliation>
    </creator>
    <creator>
      <creatorName>Celik, Ufuk</creatorName>
      <givenName>Ufuk</givenName>
      <familyName>Celik</familyName>
      <affiliation>Ege Univ, Fac Fisheries, TR-35100 Izmir, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>An In Vitro And In Silico Study On The Antioxidant And Cell Culture-Based Study On The Chemoprotective Activities Of Fish Muscle Protein Hydrolysates Obtained From European Seabass And Gilthead Seabream</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2019</publicationYear>
  <dates>
    <date dateType="Issued">2019-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/67903</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.foodchem.2018.08.004</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">European seabass (Dicentrarchus labrax, Linnaeus, 1758) (L) and gilthead seabream (Spares aurata, Linnaeus, 1758) (C) muscles were hydrolysated by Alcalase (L-alc, C-alc) and Chymotrypsin (L-ch, C-ch) then hydrolysates were examined and their peptide profiles obtained. A total of 765, 794, 132 and 232 peptides were identified in C-alc, L-alc, C-ch, and L-ch, respectively. Although, L-ch and C-ch, were expected to have more antioxidant capacity because of their peptide profiles, Alcalase hydrolysates observed in vitro, were slightly higher (TEAC assay for C-alc: 848.11 +/- 60.78 cool TE/g protein). Maximum inhibition of oxidative stress was determined for L-alc (12.8% +/- 4.5%) in MDCK1 cell lines. Highest proliferative capacity observed for C-alc (147.0% +/- 3.1%) at MTT assay in MDCK1 cell culture. L-ch showed the highest chemopreventive effect with a 40-60% decrease for human colon adenocarcinoma cell line HT-29. This research points out the importance of aquatic sources as raw materials for peptide researches.</description>
  </descriptions>
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