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Determination of VP2 sequence-based virulence motifs and phylogenetic analysis of domestic Turkish IPNV isolates

Tamer, Cuneyt; Isidan, Hakan; Kalayci, Gulnur; Ozan, Emre; Ozkan, Buket; Albayrak, Harun


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{
  "@context": "https://schema.org/", 
  "@id": 238446, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Ondokuz Mayis Univ, Fac Vet Med, Dept Virol, TR-55200 Atakum, Samsun, Turkey", 
      "name": "Tamer, Cuneyt"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Sivas Cumhuriyet Univ, Fac Vet Med, Dept Virol, Sivas, Turkey", 
      "name": "Isidan, Hakan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Republ Turkey Minist Agr & Forestry, Izmir Bornova Vet Control Inst, Izmir, Turkey", 
      "name": "Kalayci, Gulnur"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ondokuz Mayis Univ, Fac Vet Med, Dept Vet Expt Anim, Samsun, Turkey", 
      "name": "Ozan, Emre"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Republ Turkey Minist Agr & Forestry, Izmir Bornova Vet Control Inst, Izmir, Turkey", 
      "name": "Ozkan, Buket"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ondokuz Mayis Univ, Fac Vet Med, Dept Virol, TR-55200 Atakum, Samsun, Turkey", 
      "name": "Albayrak, Harun"
    }
  ], 
  "datePublished": "2022-01-01", 
  "description": "Infectious pancreatic necrosis (IPN) is a highly contagious disease of young salmonid fish and is one of the most severe economic diseases in aquaculture. In Turkey, an increase in infectious pancreatic necrosis virus (IPNV) outbreaks in freshwater rainbow trout have been reported in recent years. This study aimed to analyze the VP2 gene from recent IPNV isolates from Turkey to determine whether there are epidemiological links between IPNV isolates from rainbow trout (Oncorhynchus mykiss; 62) and sea bass (Dicentrarchus labrax; 1), wild turbot (Scophthalmus maximus; 1) and the environment in order to investigate potential wild and farmed fish interactions. In this study, 62 Turkish IPNV isolates collected over 10 years (2005-2014) from rainbow trout, sea bass and turbot were genotypically characterized. The phylogenetic analysis indicated that Turkish IPNV isolates are closely related to strains from Denmark, Iran and Spain and that all Turkish IPNV isolates belong to genogroup V, serotype A2 (Sp strain). Furthermore, low genetic diversity was found among the Turkish isolates (identity, 95.5%-100% nucleotides and 97.8%-100% amino acids). The result of the analysis of the amino acid residues found at positions 217, 221 and 247 (proline, threonine and alanine, respectively) could be associated with virulence.", 
  "headline": "Determination of VP2 sequence-based virulence motifs and phylogenetic analysis of domestic Turkish IPNV isolates", 
  "identifier": 238446, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Determination of VP2 sequence-based virulence motifs and phylogenetic analysis of domestic Turkish IPNV isolates", 
  "url": "https://aperta.ulakbim.gov.tr/record/238446"
}
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