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Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes

Kasimogullari, Rahmi; Bulbul, Metin; Mert, Samet; Guleryuz, Hulya


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        "affiliation": "Dumlupinar Univ, Fac Arts & Sci, Dept Chem, Kutahya, Turkey", 
        "name": "Kasimogullari, Rahmi"
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      {
        "affiliation": "Dumlupinar Univ, Fac Arts & Sci, Dept Chem, Kutahya, Turkey", 
        "name": "Bulbul, Metin"
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      {
        "affiliation": "Dumlupinar Univ, Fac Arts & Sci, Dept Chem, Kutahya, Turkey", 
        "name": "Mert, Samet"
      }, 
      {
        "affiliation": "Dumlupinar Univ, Fac Arts & Sci, Dept Chem, Kutahya, Turkey", 
        "name": "Guleryuz, Hulya"
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    "description": "In this study, some novel inhibitors were synthesised from the further stage reactions of 4-benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carbonyl chloride with 5-amino-1,3,4-thiadiazole-2-sulphonamide 1 (inhibitor 1). They were characterised by elemental and spectral (", 
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