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Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes

Kasimogullari, Rahmi; Bulbul, Metin; Mert, Samet; Guleryuz, Hulya


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{
  "DOI": "10.3109/14756366.2010.491795", 
  "abstract": "In this study, some novel inhibitors were synthesised from the further stage reactions of 4-benzoyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole-3-carbonyl chloride with 5-amino-1,3,4-thiadiazole-2-sulphonamide 1 (inhibitor 1). They were characterised by elemental and spectral (", 
  "author": [
    {
      "family": "Kasimogullari", 
      "given": " Rahmi"
    }, 
    {
      "family": "Bulbul", 
      "given": " Metin"
    }, 
    {
      "family": "Mert", 
      "given": " Samet"
    }, 
    {
      "family": "Guleryuz", 
      "given": " Hulya"
    }
  ], 
  "container_title": "JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY", 
  "id": "21543", 
  "issue": "2", 
  "issued": {
    "date-parts": [
      [
        2011, 
        1, 
        1
      ]
    ]
  }, 
  "page": "231-237", 
  "title": "Synthesis of 5-amino-1,3,4-thiadiazole-2-sulphonamide derivatives and their inhibition effects on human carbonic anhydrase isozymes", 
  "type": "article-journal", 
  "volume": "26"
}
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