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Development of Multi Scale Structured Al/Al2O3 Nanowires for Controlled Cell Guidance

Lee, Juseok; Miro, Marina M.; Akkan, Cagri K.; Haidar, Ayman; Metzger, Wolfgang; Schwarz, Lukas K.; Zaporojtchenko, Vladimir; Schaefer, Karl H.; Abdul-Khaliq, Hashim; Veith, Michael; Aktas, Cenk


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/14719</identifier>
  <creators>
    <creator>
      <creatorName>Lee, Juseok</creatorName>
      <givenName>Juseok</givenName>
      <familyName>Lee</familyName>
      <affiliation>Leibniz Inst New Mat, D-66123 Saarbrucken, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Miro, Marina M.</creatorName>
      <givenName>Marina M.</givenName>
      <familyName>Miro</familyName>
      <affiliation>Leibniz Inst New Mat, D-66123 Saarbrucken, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Akkan, Cagri K.</creatorName>
      <givenName>Cagri K.</givenName>
      <familyName>Akkan</familyName>
      <affiliation>Leibniz Inst New Mat, D-66123 Saarbrucken, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Haidar, Ayman</creatorName>
      <givenName>Ayman</givenName>
      <familyName>Haidar</familyName>
      <affiliation>Univ Saarland, Clin Pediat Cardiol, D-66421 Homburg, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Metzger, Wolfgang</creatorName>
      <givenName>Wolfgang</givenName>
      <familyName>Metzger</familyName>
      <affiliation>Univ Saarland, Dept Trauma Hand &amp; Reconstruct Surg, D-66421 Homburg, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Schwarz, Lukas K.</creatorName>
      <givenName>Lukas K.</givenName>
      <familyName>Schwarz</familyName>
      <affiliation>Univ Appl Sci Kaiserslautern, D-66482 Zweibrucken, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Zaporojtchenko, Vladimir</creatorName>
      <givenName>Vladimir</givenName>
      <familyName>Zaporojtchenko</familyName>
      <affiliation>Univ Kiel, Fac Engn, Chair Multicomponent Mat, D-24143 Kiel, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Schaefer, Karl H.</creatorName>
      <givenName>Karl H.</givenName>
      <familyName>Schaefer</familyName>
      <affiliation>Univ Appl Sci Kaiserslautern, D-66482 Zweibrucken, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Abdul-Khaliq, Hashim</creatorName>
      <givenName>Hashim</givenName>
      <familyName>Abdul-Khaliq</familyName>
      <affiliation>Univ Saarland, Clin Pediat Cardiol, D-66421 Homburg, Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Veith, Michael</creatorName>
      <givenName>Michael</givenName>
      <familyName>Veith</familyName>
    </creator>
    <creator>
      <creatorName>Aktas, Cenk</creatorName>
      <givenName>Cenk</givenName>
      <familyName>Aktas</familyName>
      <affiliation>Leibniz Inst New Mat, D-66123 Saarbrucken, Germany</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Development Of Multi Scale Structured Al/Al2O3 Nanowires For Controlled Cell Guidance</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2013</publicationYear>
  <dates>
    <date dateType="Issued">2013-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/14719</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1166/jbn.2013.1522</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Cell responses to surface and contact cell guidance are of great interest in bio-applications especially on nano- and micro scale features. Recently we showed selective cell responses on Al/Al2O3 bi-phasic nanowires (NWs). In this context, Al/Al2O3 NWs were synthesized by the chemical vapor deposition of ((BuOAlH2)-Bu-t)(2). Afterwards, linear periodic nano- and micro structured NWs were formed using laser interference lithography (LIL) technique to study the contact guidance of neurons from rat dorsal root ganglion (DRG), human umbilical vein smooth muscle cells (HUVSMC), human umbilical vein endothelial cells (HUVEC) and human osteoblast (HOB). LIL treatment did not alter surface chemistry of NWs. From our preliminary research LIL patterned NWs lead to alignment of axons contrary to non-patterned NWs. Morphology of HUVSMC changed from poly- to linear shapes and strong alignment was observed while HUVEC and HOB were not affected.</description>
  </descriptions>
</resource>
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