1 Ocak 2017 Dergi makalesi Açık Erişim

Unal, Betul; Yalcinkaya, Esra Evrim; Gumustas, Sila; Sonmez, Burak; Ozkan, Melek; Balcan, Mehmet; Demirkol, Dilek Odaci; Timur, Suna

Dublin Core

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  <dc:creator>Unal, Betul</dc:creator>
  <dc:creator>Yalcinkaya, Esra Evrim</dc:creator>
  <dc:creator>Gumustas, Sila</dc:creator>
  <dc:creator>Sonmez, Burak</dc:creator>
  <dc:creator>Ozkan, Melek</dc:creator>
  <dc:creator>Balcan, Mehmet</dc:creator>
  <dc:creator>Demirkol, Dilek Odaci</dc:creator>
  <dc:creator>Timur, Suna</dc:creator>
  <dc:date>2017-01-01</dc:date>
  <dc:description>In catalytic biosensors, the immobilization of biomolecules in a suitable matrix is one of the vital parameters for obtaining improved systems. Clays, which are intercalated with various organic compounds, have a great tendency to develop biosensors with high stability, sensitivity and reproducibility. Herein, a polymer/clay nanocomposite based on natural silicate montmorilonite (Mt) and a biodegradable polymer polyglycolide (PGA) was prepared and characterized by FT-IR, thermogravimetric analysis, differential thermogravimetric analysis and X-ray diffraction. Then, the resulting matrix was used as a fixation matrix for pyranose oxidase (POx), which was selected as a model enzyme. The bioactive layer was fabricated by immobilization of POx on glassy carbon electrodes by means of PGA-Mt and bovine serum albumin. The POx biosensor revealed a good linear range from 0.01 to 0.5 mM glucose with a LOD of 1.2 mM. After the optimization of the working and preparation conditions, characterization studies were performed for glucose detection. Finally, the PGA-Mt/POx biosensor was confirmed to have detected glucose in beverages without needing any sample pre-treatment.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/111096</dc:identifier>
  <dc:identifier>oai:zenodo.org:111096</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>NEW JOURNAL OF CHEMISTRY 41(17) 9371-9379</dc:source>
  <dc:title>Polyglycolide-montmorillonite as a novel nanocomposite platform for biosensing applications</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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