1 Ocak 2017 Dergi makalesi Açık Erişim

Unal, Betul; Yalcinkaya, Esra Evrim; Gumustas, Sila; Sonmez, Burak; Ozkan, Melek; Balcan, Mehmet; Demirkol, Dilek Odaci; Timur, Suna

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{
  "@context": "https://schema.org/", 
  "@id": 111096, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Sci, Dept Biochem, TR-35100 Bornova, Turkey", 
      "name": "Unal, Betul"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Sci, Dept Chem, TR-35100 Bornova, Turkey", 
      "name": "Yalcinkaya, Esra Evrim"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Sci, Dept Chem, TR-35100 Bornova, Turkey", 
      "name": "Gumustas, Sila"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Sci, Dept Biochem, TR-35100 Bornova, Turkey", 
      "name": "Sonmez, Burak"
    }, 
    {
      "@type": "Person", 
      "affiliation": "IZTECH Fac Sci, Dept Chem, TR-35340 Urla Izmir, Turkey", 
      "name": "Ozkan, Melek"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Sci, Dept Chem, TR-35100 Bornova, Turkey", 
      "name": "Balcan, Mehmet"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Sci, Dept Biochem, TR-35100 Bornova, Turkey", 
      "name": "Demirkol, Dilek Odaci"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Ege Univ, Fac Sci, Dept Biochem, TR-35100 Bornova, Turkey", 
      "name": "Timur, Suna"
    }
  ], 
  "datePublished": "2017-01-01", 
  "description": "In catalytic biosensors, the immobilization of biomolecules in a suitable matrix is one of the vital parameters for obtaining improved systems. Clays, which are intercalated with various organic compounds, have a great tendency to develop biosensors with high stability, sensitivity and reproducibility. Herein, a polymer/clay nanocomposite based on natural silicate montmorilonite (Mt) and a biodegradable polymer polyglycolide (PGA) was prepared and characterized by FT-IR, thermogravimetric analysis, differential thermogravimetric analysis and X-ray diffraction. Then, the resulting matrix was used as a fixation matrix for pyranose oxidase (POx), which was selected as a model enzyme. The bioactive layer was fabricated by immobilization of POx on glassy carbon electrodes by means of PGA-Mt and bovine serum albumin. The POx biosensor revealed a good linear range from 0.01 to 0.5 mM glucose with a LOD of 1.2 mM. After the optimization of the working and preparation conditions, characterization studies were performed for glucose detection. Finally, the PGA-Mt/POx biosensor was confirmed to have detected glucose in beverages without needing any sample pre-treatment.", 
  "headline": "Polyglycolide-montmorillonite as a novel nanocomposite platform for biosensing applications", 
  "identifier": 111096, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Polyglycolide-montmorillonite as a novel nanocomposite platform for biosensing applications", 
  "url": "https://aperta.ulakbim.gov.tr/record/111096"
}